Mike Wood

I beg to move, That this House has considered World Sepsis Awareness Month. As co-chair of the all-party parliamentary group on sepsis, I would like to begin by expressing my gratitude to the Backbench Business Committee for granting time for this debate. To the best of my knowledge, this is the very first debate in the House of Commons Chamber dedicated to sepsis. In the past, this devastating condition has been discussed only in Westminster Hall debates or raised through brief interventions and questions. Having sepsis debated on the Floor of the main Chamber during Sepsis Awareness Month is a major milestone, not only for Parliament but for the clinicians, charities and bereaved families across the country who have campaigned tirelessly to bring this condition out of the shadows. I would also like to thank the co-sponsors of this debate: the hon. Member for Ashfield (Lee Anderson), who cannot be here this afternoon but who led an important Westminster Hall debate on this subject two years ago, and the hon. Member for Dartford (Jim Dickson), vice-chair of the APPG. Sepsis strikes indiscriminately, ruthlessly and with terrifying speed, without regard for background, class or, indeed, political allegiance. It is vital that we all stand united in our determination to tackle this deadly condition. It is a challenge that completely transcends party politics. On Sunday, communities across the world marked World Sepsis Day. The international theme for this year could not be more apt: “Invest in Sepsis—Save Lives.” The World Health Organisation recognises sepsis as one of the leading causes of death and disability globally, estimating that sepsis-related illnesses account for one in every five deaths worldwide. In the United Kingdom, NHS England has made it clear that sepsis claims more lives each year than lung cancer and represents the second biggest killer in our hospitals after cardiovascular disease. Every single year, an estimated 245,000 people in the UK develop sepsis and, tragically, more than 48,000 lose their lives. That is a higher annual death toll than bowel, breast and prostate cancers combined. Behind every one of those figures is a family left grieving and asking the same agonising question: what if? What if the symptoms had been recognised an hour earlier? What if antibiotics had been administered sooner? What if someone had simply asked, “Could it be sepsis?”? Madam Deputy Speaker, as you know, I do not approach this debate purely as a parliamentarian dispassionately analysing policy responses to one of the leading causes of avoidable death. I stand in this Chamber today because almost a decade ago, by the grace of God and the extraordinary skill and care of NHS staff, my life was saved. In January 2017, I was a relatively fit and active 40-year-old Member of Parliament. I had developed what I assumed was merely a winter infection. Like many people would, I assumed that I could push through it, take some paracetamol and carry on working. I travelled out to Strasbourg to take part in the Parliamentary Assembly of the Council of Europe on the Sunday evening, but within days my condition collapsed. An ordinary throat infection triggered a catastrophic immune response. My body, in attempting to fight the infection, began attacking its own tissues and organs. By Thursday, after seeing a French GP, I flew back to Britain. On Friday, I attended the official launch of the local enterprise zone that I had campaigned hard for in my constituency, but as soon as I arrived there I was so ill that I had to rest in the back room. On Saturday morning, I got out of bed, started putting my suit on over my pyjamas and told my wife Laura that I had to come down to Westminster to vote. Like many in politics, my behaviour can at times appear to some people to be a little idiosyncratic; fortunately, Laura realised that, even for a Member of Parliament, that was not entirely normal behaviour. Laura rushed me to Russells Hall hospital in Dudley, where my blood pressure plummeted into septic shock and my organs began shutting down. My life was hanging by a thread. The medical team had to place me in a medically induced coma. Doctors told my family that my chances of pulling through were no better than one in 10. For 11 days, I lay in intensive care on life support—or, as my family sometimes remind me, I slept through the difficult bits. When I did finally wake up, my muscles had wasted away—I could barely lift my arms, let alone stand or walk—but it could easily have been so much worse. What if Laura had left me to get some rest that Saturday morning while she took our daughter to her dance class? Above all, what if the nurse who examined me at the accident and emergency department had not had the insight to check whether the symptoms, which could easily have been mistaken for other illnesses such as flu or meningitis, might be sepsis? I owe a debt of gratitude to the doctors, intensive care nurses and other staff at Russells Hall hospital that I can never repay, but as long as I have the honour of serving in this House, I will use my voice to fight for sepsis patients and their families. There is a common misconception that sepsis is primarily the result of hospital-acquired infection, but the evidence demonstrates the exact opposite. A major 2024 population study led by Professor van Staa, analysing linked primary care and hospital data in England, showed that the vast majority of sepsis cases are community acquired, developing in homes, workplaces and local communities long before a patient reaches an acute hospital bed. That research also uncovered deep health inequalities in sepsis risk. The risk of developing sepsis is significantly heightened by socioeconomic deprivation, by frailty, by being housebound and by chronic conditions such as cancer, diabetes and learning disabilities. Exposure to antibiotics in the previous two months was also identified as a strong risk factor. While ethnicity was not an independent biological factor, black and Asian individuals suffer from a higher prevalence of predisposing conditions including diabetes, chronic liver disease and severe anaemia, which puts them at a greater risk, so tackling sepsis is not merely a technical, clinical issue but a fundamental challenge of health inequality and community prevention. One of the most critical clinical lessons learned in recent years is the direct link between viral infections and sepsis. For decades, the public and the medical community viewed sepsis almost exclusively as a bacterial complication, but the covid-19 pandemic demonstrated that viral infections can trigger the exact same catastrophic septic response. The overwhelming cytokine storms, microvascular clotting and rapid progression to acute respiratory distress syndrome and multi-organ failure seen in covid intensive care units are classic manifestations of viral sepsis. It is thought by many experts in the field that the vast majority of covid deaths were a direct result of septic reactions. Sepsis is not defined by the pathogen; it is defined by the body’s life-threatening immune reaction to any severe infection, whether bacterial, viral or fungal. That reality extends directly into long-term recovery: millions who had covid-19 are still living with long covid. Sepsis survivors have known that reality for generations under the name of post-sepsis syndrome. In my case, it is little more than some nerve damage and tiredness, even a decade later, but for many the symptoms are more severe. Up to 50% of sepsis survivors suffer prolonged physical, cognitive and psychological impairments from debilitating fatigue and cognitive brain fog to severe muscle weakness and post-traumatic stress disorder. The clinical insights gained from viral sepsis during the pandemic must now be used to build integrated recovery pathways for all sepsis survivors. To curb preventable deaths, a health system must act decisively in several areas; in the interests of time, I will go through just four. First, the system must ensure consistent rapid recognition. Time is the single most decisive factor in sepsis survival. Clinical research shows that administering appropriate antibiotics within the first hour of a patient presenting to an emergency department with sepsis reduces the risk of death by a full one third compared with delayed treatment. Secondly, the system must ensure that where sepsis is suspected, appropriate clinical escalation pathways are in place. Where sepsis is suspected, early warning systems such as the national early warning score 2, or NEWS2, have saved countless lives, and the ongoing roll-out of Martha’s rule across NHS trusts, which has already saved thousands of lives, is vital in ensuring that patients and loved ones can trigger an immediate independent critical review when they sense deterioration. Thirdly, we must take advantage of innovation in rapid diagnostics. We know that administering broad-spectrum antibiotics within the golden hour that I spoke of massively increases survival rates, but clinicians often face the dilemma of judging whether that is compatible with responsible antimicrobial stewardship. Deploying rapid molecular diagnostics, bedside biomarker technologies and wearable continuous physiological monitors can remove that guesswork, and provide targeted care before septic shock takes hold and it can be too late. Fourthly, although Britain has in many ways led the way in developing and enhancing sepsis care and treatment, we must be open to learning from established international models and practices. Sweden utilises standard sepsis alerts to prioritise patients at triage, and implements mandatory post-discharge telephone follow-ups. France, where I was when I was taken ill, has since introduced an integrated national sepsis plan spanning pre-hospital recognition, emergency pathways and structured rehabilitation to help patients return to employment. Australia established a national sepsis clinical care standard built around seven quality statements, ensuring end-to-end consistency from triage through to survivorship. The publication in July of the sepsis modern service framework by NHS England and the Department of Health and Social Care is an important step towards doing that and learning the lessons from around the world; I warmly welcome it. The framework is one of the first to be published under the 10-year health plan. Its headline goal, “to reduce deaths, severe complications and long-term harm from sepsis…by at least 25% by 2035” is a target that every member of this House can endorse.